Biostatistics is one of the scientific fields for which the developments during the last decades of the 20th century have been the most important. Biostatistics is a pluri-disciplinary area combining statistics and biology, but also agronomics, medicine or health sciences. It needs a good knowledge of the mathematical background inherent in statistical methodology, in order to understand the various fields of applications. The idea of this book is to present a variety of research papers on the state of art in modern biostatistics. Biostatistics is interacting with many scientific fields. To highlight this wide diversity, we deliberately put these interactions at the center of our project.

Our book is therefore divided into two parts. Part I is presenting several statistical models and methods for different biologic applications, while Part II will be concerned with problems and statistical methods coming from other related scientific fields.

This book intends to provide a basis for many people interested in biostatistics and related sciences. Students, teachers and academic researchers will find an overview on modelling and statistical analysis of biological data. Also, the book is meant for practicioners involved in research organisations (pharmacologic industry, medicine, food industry,..) for which statistics is an indispensable tool.